Wednesday 1 February

Breakfast career panel

8.30 – 9.10 Keynote

Prof. Bart Vanhaesebroeck, “In search of novel ways to modulate the PI3K pathway for therapeutic benefit”

9.10 – 11.45 Session Venous/Lymphatic Malformations and PI3K signaling

9.10 – 9.40        Prof. Mariona Graupera, “Insights into the onset and progression of PIK3CA-related vascular malformations”                                   

9.40 – 9.55        short talk

9.55 – 10.25      Prof. Taija Mäkinen, “Pathogenic mechanisms of lymphatic malformations”

10.25 – 10.40     short talk

coffee break

11.00 – 11.30      Prof. Guillaume Canaud, “Targeted therapies in PIK3CA-related vascular anomalies”                                          

11.30 – 11.45     short talk

Lunch and poster session 1

Patient testimony

13.45 –  14.25     Keynote

Elisabeth Tournier-Lasserve, “Deciphering the complex genomic architecture of moyamoya, an avenue towards the pathophysiology of this mysterious cerebral angiopathy”

14.25 – 17.10 Session Cerebral Cavernous Malformations (CCMs) & MAP3K3 signaling

14.25 – 14.55     Prof. Douglas Marchuk, “Somatic mutations drive the development and growth of Cerebral Cavernous Malformations”

14.55 – 15.10     short talk

15.10 – 15.40     Prof. Salim Seyfried, “Studying the role of biomechanics in vascular disease models in zebrafish”

15.40 – 15.55     short talk

coffee break

16.25– 16.55       Prof. Roberto Latini, “How can preclinical research help CCM patients: focus on two cases, propranolol and atorvastatin”

16.55– 17.10       short talk

17.15 – 18.00  Career session

Speakers’ dinner

Others: free evening